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What are Ethosomes and how do they work?

What are Ethosomes and how do they work?

What are Ethosomes and how to they work?

Ethosomes are the latest advancements in Korean skincare transdermal delivery systems that enable ingredients to be absorbed into the deeper layers of the skin. With high concentrations of ethanol – it creates the ability to disrupt the skin’s lipid bilayer giving it the ability to penetrate the stratum corneum & the hair follicles. The word Ethosome is a combination of the word ethanol and liposomes, When the two ingredients combine they works as a carrier that excels the delivery of the active ingredients deeper into the skin cells.

Ethosomes are non-toxic, double layered lipid components - they have a high drug loading capacity, improving the overall capacity to deliver ingredients deep into the skin cells. Ethosomes can help stabilize the vesicles and protect them from degradation. Ethosomes increases the fluidity and permeability of the cell membrane therefore allowing the drug/actives to reach the underlying tissue and increase the efficacy of the treatment.

Isov has developed several High Definition Ethosomes Serums

HD Ethosome Skin Boosting Act Serum

  • Containing 5 Complex Peptides -building strong elastin and wrinkle care through collagen synthesis promotion.

  • Arginine- (Amino Acid) – This powerful hydrating ingredient locks in moisture and protects against free radicals, Improves skin circulation, barrier and anti-inflammatory properties.

  • Carnosine – Increases the fibroblast cells to synthesize collagen, reduces the signs of aging, glycation and improves skins texture.

Tips – In treatment room, perform a skin boosting facial massage before applying 2- 3 layers of serum. Great tip for those with glycation and texture issues. Allow product to absorb and finish with finishing products.

Ideal for Aging skin, Dry skin types, Loss of Volume, Dull skin

HD Ethosome Skin Brightening ACT Serum

  • Tranexamic Acid- (latest Tyrosinase inhibitor) a lysine (Amino Acid) derivative. Tranexamic acid alters the way cells produce melanin by interrupting pathways in the skin.

  • Niacinamide – Reduces environmental damage by improving the skin barrier – also contains brightening and hydrating capabilities.

  • Ascorbyl Glucoside A Vitamin C derivative – Lightens and brightens dull complexion and enhances skin radiance, helps diminish fine lines and can help boost your sunscreens effectiveness.

Tips – In treatment room, perform lymphatic drainage massage prior to applying product for skin toning properties. Great to be layered with HD Ethosome Blue Energy for inner skin hydration & tone improvement.

Ideal for Early Pigmentation, Dull skin, Dry & Rough skin

HD Ethosome Blue Energy Serum

  • Phyto Exosome

  • Resveratrol – Retinol alternative fights against aging, naturally occurring antioxidant. Slows aging of the skin, stimulates healthy cell proliferation. Reduces redness & even skin tones.

  • Copper Tripeptide -1 – Supports the function of healthy skin cells with water binding glycosaminonglycans. Helps fortify the skins structural integrity and reduces the appearance of lines and wrinkles and skin sagging.

  • Trehalose – Antioxidant that protects skin from free radical damage, water binding, hydrating properties.

Tips – Great for post facial procedure for its cooling and calming properties, can be layered with HD Ethosome Vitamin B Serum

 Ideal for Inflammatory and troubled skin, oily skin, dehydrated skin.

HD Ethosome Pink Energy Serum

  • Ocean Tannin Exosome – Healing abilities, tannin contains antifungal, antibacterial, antioxidant.

  • PDRN – Salmon DNA – improves skin repair by vascular endothelial growth factors. Improves skins texture, collagen levels. Stimulates repair and growth of fibroblast.

  • Bifida Fermented Filtrate – A hero probiotic in skin care, strengthens skin’s immunity, soothes inflammation, lessens skins sensitivity.

Tips – Use as a first essence post procedure or sun exposure to calm and soothe skin, Pairs well with Blue HD by layering.

Ideal for sensitive skin types, skin in need of soothing and post procedure.  

HD Ethosome Time Reset Serum

  • Retinol HPR – As powerful as a prescribed retinol without the unwanted side effects such as flaking, redness and skin irritation. Collagen boosting, increases cell turn over, aides in acne correction.

  • Ceramide – Improves skin barrier, protects skin from harmful substances. Prevents TEWL by holding water in the skin.

  • Centella Asiatica Extract (AKA Cica) – Improves acne and other inflammatory skin conditions – strong wound healing capabilities.

Tips Great for laying with Brightening ACT serum for overnight repair.

Ideal for skin with enlarged pores, sagging and skin in need of elasticity care.

HD Ethosome Vitamin C Serum

  • Ascorbic Acid – Pure Vitamin C, proven to reduce wrinkles and skin discoloration, helps boost effectiveness of sunscreen, most abundant antioxidants

  • Tocopheryl Acetate -Vitamin E – Antioxidant that prevents free radical damage from sun exposure

  • Ferulic Acid – Protects the skin from sun exposure and fades dark spots, High in antioxidants, fights free radicals. Known to reduce tyrosinase activity.

  • Ascorbyl Tetraisopalmitate – Oil soluble Vitamin C – speeds up cellular turnover, lightens both PIH & PIE

  • Magnesium Ascorbyl Phosphate – Stabilized form of Vitamin C, reduces fine lines, skin tone and texture

Tips For sensitive skin – start with a small amount every 2-3 days and gradually increase as the skin adapts.

Ideal for skin with pigmentation, dull skin, skin in need of antioxidants

HD Ethosome Vitamin B Serum

  • Vitamin B Complex – 8 Amino Acid – Strengthens skins immunity and maintaining barrier layer. Promotes growth of new cells, healing damaged skin.

  • Jojoba Seed Oil – Intensely hydrating and adds moisture to skin barrier.

  • Betaine – Skin plumping, with anti-inflammation properties – calms acne flair ups.

Tips Can be multi layered with Skin Boosting Act serum.

Ideal for troubled skin, dehydrated skin, skin with barrier issues


Multi Layering Recommendation

For Energizing & Mature Skin

HD Vit C + HD Time Reset (apply Vit C then time reset)

For Glass Skin Recipe

HD Vit C =+ Pink Energy


Youth & Firming

HD Skin Boosting Act Serum + Time Reset (apply Skin boosting followed by time reset)

For Elastic Recovery Recipe

Skin Boosting Act HD + Vit B HD


Troubled Skin

HD Blue Energy + Multi B HD (apply Blue energy HD followed by HD Vit B)

For Clearing Recipe

HD Blue Energy + HD Time Reset

Hormonal Issues

HD Blue Energy + Pink Energy

For Dewy Skin

HD Skin Brightening Act + HD Pink Energy

Immune & Barrier

HD Vit B + HD Time Reset

Re-Volumnizing Barrier

HD Time Reset + HD Pink Energy



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